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Search Results for " cortical cell "

11

Compounds

Cat No. Product Name Synonyms Targets
T12472 Pifithrin-α, p-Nitro, Cyclic PFN-α p53
Pifithrin-α, p-Nitro, Cyclic (PFN-α) (PFN-α) is cell-permeable and active-form inhibitor of p53.
T22517 5,7-Dichlorokynurenic acid 5,7-dichlorokynurenic acid sodium,5,7-DCKA NMDAR
5,7-Dichlorokynurenic acid (5,7-dichlorokynurenic acid sodium) is an NMDA receptor antagonist.
T36141 Boscalid Mitochondrial Metabolism
Boscalid is a broad-spectrum carboxamide fungicide that inhibits fungal respiration by binding to the ubiquinone site of mitochondrial complex II/succinate dehydrogenase.1It suppresses mycelial growth ofS. minorby 87 to ...
T83288 5-Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone
Hydroxy-2-[2-(2-hydroxyphenyl)ethyl]chromone is a neuroprotective agent that exhibits marked neuroprotective activity by mitigating glutamate-induced neurotoxicity in primary rat cortical cell cultures [1].
T69429 Y27632 HCl hydrate
Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepa...
TN3771 Dasycarpol Others
Dasycarpol(9beta-Hydroxyfraxinellone) shows significant neuroprotective activity against glutamate-induced neurotoxicity in primary cultures of rat cortical cells at a concentration of 0.1 microM. Dasycarpol also shows m...
T36516 RC574 RC574
RC574 is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic agent probucol .1It inhibits glutamate-induced cell death in HT22 cells (IC50= 276.2 nM) and mouse primary cortical neurons...
T37476 Cyclo(L-Phe-L-Val)
Cyclo(L-Phe-L-Val) is a metabolite of the sponge bacterium Pseudoalteromonas sp. NJ6-3-1 that can autoinduce production of antibacterial substances active against S. aureus when co-cultured at a low cell density. It indu...
T36570 KUS121
KUS121 is a valosin-containing protein (VCP) modulator that inhibits VCP ATPase activity (IC50= 330 nM).1It inhibits cell death, ATP depletion, and upregulation of C/EBP-homologous protein (CHOP) induced by tunicamycin, ...
T36903 Rasagiline-13C3 (mesylate) Rasagiline-13C3 (mesylate)
Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is se...
T83825 Trofinetide acetate NNZ-2566
Trofinetide, derived from the neuroprotective tripeptide Gly-Pro-Glu (an N-terminal sequence of insulin-like growth factor-1, IGF-1), shows promise in various neuroprotective models. At a concentration of 10 nM, it mitig...
TargetMol